you're reading...

Hyoscyamus niger

Hyoscyamus niger                          Common name:  Henbane
Family: Solanaceae

Parts used:  Leaves and flowering tops

Constituents: Tropane alkaloids (0.045%-0.14%):  hyoscyamine, hyoscine [scopolamine]

Medicinal actions: Antispasmodic, anodyne, sedative, mydriatic


Medicinal use: Hyoscyamus is often compared to Belladonna as both plants exert anticholinergics effects. Hyoscyamus is most often used for its antispasmodic effects on the digestive and urinary tracts, (eg. kidney stones) with large doses affecting the central nervous system.


  • Tropane alkaloids (hyoscyamine & scopolamine) are negatively cholinergic & positively adrenergic (sympathomimetic), causing an inhibition of parasympathetic and stimulation of sympathetic nerves via competitive inhibition of acetylcholine. Effects lead to increased intraocular pressure & dipolpia, reduction of bodily secretions, inhibition of vagus nerve (tachycardia, increased cardiac output and raised blood pressure), reduced tone in all smooth muscles: vasodilation, bronchial dilation, reduced peristalsis.

Pharmacy:  Tincture (1:10, 45%), take 10 drops twice a day to a max of 1 ml. Increase by 1 drop every three days until dry mouth and visual disturbances appear. Reduce by 1 drop each day until side effects disappear. Weekly max 10ml.

Toxicity: First sign of toxicity is dry mouth & eyes. Acute: Facial dryness, nausea, increased pulse rate, vertigo, dull headache, dilated pupils, muscular weakness, reduced peristalsis, tachycardia, paralysis, delirium and hallucinations, coma, spasms, cramps, convulsions, rapid pulse, salivation, death. Chronic: macular rash which is dry and pruritic.


Comments are closed.

NPLEX II Herbal Review Course

Are you writing NPLEX II this summer?

Join me for an (as fun as possible!) day of herbal learning, meant to save you study time and build your confidence in answering exam-like questions about botanical medicine for your upcoming NPLEX II exam.

Wednesday July 7th 10am – 2pm PST


A place for all things herbal medicine

Created and maintained with love by Dr. Marisa Marciano, ND



This site is created and maintained as a free resource for herb lovers around the world. Donations are accepted with gratitude :)


Get my new book here!

The Botanical Medicine Manual is the best multidisciplinary, integrated guide available for students, clinicians & instructors. This book gives top quality content that you will refer to often in class, for board exams & in practice. Topics include, study tips, Botanical Actions, Constituents, Pharmacy, Monographs, Nutrition, Carbohydrates, Proteins, Fats, Fiber and much more evidence informed medicine. Cost is $39.95