Parts used: Leaves and flowering tops
Constituents: Tropane alkaloids (0.045%-0.14%): hyoscyamine, hyoscine [scopolamine]
Medicinal actions: Antispasmodic, anodyne, sedative, mydriatic
Medicinal use: Hyoscyamus is often compared to Belladonna as both plants exert anticholinergics effects. Hyoscyamus is most often used for its antispasmodic effects on the digestive and urinary tracts, (eg. kidney stones) with large doses affecting the central nervous system.
Pharmacy: Tincture (1:10, 45%), take 10 drops twice a day to a max of 1 ml. Increase by 1 drop every three days until dry mouth and visual disturbances appear. Reduce by 1 drop each day until side effects disappear. Weekly max 10ml.
Toxicity: First sign of toxicity is dry mouth & eyes. Acute: Facial dryness, nausea, increased pulse rate, vertigo, dull headache, dilated pupils, muscular weakness, reduced peristalsis, tachycardia, paralysis, delirium and hallucinations, coma, spasms, cramps, convulsions, rapid pulse, salivation, death. Chronic: macular rash which is dry and pruritic.