Thuja occidentalis Common name: Thuja, White Cedar
Part used: Leaf & Bark
Constituents: Polysaccharides & glycoprotein, Volatile oil (1.4-4%): thujone (alpha-thujone, 59%), (beta-thujone, 7-10%), fenchone (10-15%), Flavonoids (quercitin, amentoflavone)
Actions: Antiseptic, Immune stimulant, Emmenagogue
- Is used for respiratory tract infections including Strep throat and bronchitis.
- In conjunction with antibiotics has been used in the treatment of bacterial skin infections and Herpes Simplex Virus.
- Used in external applications for treating warts, pains in the joints, arthritis and muscular rheumatism.
- Stem bark of showed strong inhibitory effects on Epstein-Barr virus early antigen activation. Was also found to exhibit the excellent anti-tumor promoting activity in two-stage mouse skin cancer.
- Polysaccharides were shown to be an inducer of the CD4+ cells in human peripheral blood. It was also demonstrated to be a potent inhibitor of the expression of HIV-1-specific antigens and of the HIV-1-specific reverse transcriptase.
- Induces IL-1 beta, IL-2, IL-3, IL-6, gamma-IFN, G-CSF, GM-CSF, and TNF-beta production in PBL cultures; and IL-1 beta and IL-6 in monocyte/ macrophage cultures.
Pharmacy: Pulse dosing internal (due to thujone). Topical Use.
Contraindications: Pregnancy due to emmenagogue and abortifacient effects (empirical).
Toxicity: EO causes cramping & GI distress. Caution against prolonged use due to cumulative toxicity of thujone (neurotoxic).